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      PDB | 5u1x ATP-gated P2X7 ion channel bound to allosteric antagonist JNJ47965567

      Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist JNJ47965567

      label Keywords
      membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state, membrane protein
      event_note Published
      11/20/2024
      blur_on Resolution
      3.201 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      2-acetamido-2-deoxy-beta-D-glucopyranose, N-{[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methyl}-2-(phenylsulfanyl)pyridine-3-carboxamide

      Original publication

      import_contacts Title
      Structural basis for subtype-specific inhibition of the P2X7 receptor.
      import_contacts Journal
      Elife 2016
      import_contacts DOI
      10.7554/eLife.22153
      person Authors
      Kawate, T., Karasawa, A.

      Read article from Elife

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Kawate, T., Karasawa, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline5u1x_default_dppc

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