PDB | 5u1w ATP-gated P2X7 ion channel bound to allosteric antagonist AZ10606120
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist AZ10606120
label Keywords
membrane protein: atp-gated ion channel: allosteric antagonist bound: closed state, membrane protein
event_note Published
11/06/2024
blur_on Resolution
3.501 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-({2-[(2-hydroxyethyl)amino]ethyl}amino)quinolin-5-yl]-2-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]acetamide
Original publication
import_contacts Title
Structural basis for subtype-specific inhibition of the P2X7 receptor.
import_contacts Journal
Elife 2016
import_contacts DOI
10.7554/eLife.22153
person Authors
Kawate, T., Karasawa, A.
copyrightData provided by Research Collaboration for Structural Biology, Kawate, T., Karasawa, A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
