PDB | 5o8f Structure of a chimaeric beta3-alpha5 GABAA receptor

Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with nanobody Nb25 and pregnanolone

label Keywords
gabaa receptor, pregnanolone, nanobody complex, neurosteroid, ion channel, membrane protein
event_note Published
11/06/2024
blur_on Resolution
3.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, Pregnanolone

Original publication

import_contacts Title
Structural basis for GABAA receptor potentiation by neurosteroids.
import_contacts Journal
Nat. Struct. Mol. Biol. 2017
import_contacts DOI
10.1038/nsmb.3484
person Authors
Miller, P.S., Masiulis, S., Scott, S., Aricescu, A.R., Steyaert, J., De Colibus, L., Pardon, E.

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