PDB | 5l1e AMPA subtype ionotropic glutamate receptor GluA2
AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor CP465022
label Keywords
transporter, membrane protein, transport protein, transport protein-inhibitor complex
event_note Published
11/13/2024
blur_on Resolution
4.37 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-2-(2-{6-[(diethylamino)methyl]pyridin-2-yl}ethyl)-6-fluoroquinazolin-4(3H)-one
Original publication
import_contacts Title
Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
import_contacts Journal
Neuron 2016
import_contacts DOI
10.1016/j.neuron.2016.08.012
person Authors
Sampson, J.M., Yelshanskaya, M.V., Singh, A.K., Sobolevsky, A.I., Kurnikova, M., Narangoda, C.
copyrightData provided by Research Collaboration for Structural Biology, Sampson, J.M., Yelshanskaya, M.V., Singh, A.K., Sobolevsky, A.I., Kurnikova, M., Narangoda, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
