PDB | 4ug2 Thermostabilised HUMAN A2a Receptor
Thermostabilised HUMAN A2a Receptor with CGS21680 bound
label Keywords
signaling protein, g seven-helix receptor, integral membrane protein, agonist bound form, thermostabilising point mutations, gpcr, 7tm receptor
event_note Published
11/13/2024
blur_on Resolution
2.6 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[P-(2-CARBOXYETHYL)PHENYLETHYL-AMINO]-5'-N-ETHYLCARBOXAMIDO ADENOSINE
Original publication
import_contacts Title
Molecular Determinants of Cgs21680 Binding to the Human Adenosine A2A Receptor.
import_contacts Journal
Mol.Pharmacol. 2015
import_contacts DOI
10.1124/MOL.114.097360
person Authors
Lebon, G., Edwards, P.C., Tate, C.G., Leslie, A.G.W.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Lebon, G., Edwards, P.C., Tate, C.G., Leslie, A.G.W. , provided free of copyright via the Protein DataBank. View original data or read license terms.
