PDB | 4ntx Structure of acid-sensing ion channel

Structure of acid-sensing ion channel in complex with snake toxin and amiloride

label Keywords
kunitz, phospholipase a2-like, ion channel, nociception, membrane, transport protein-toxin complex
event_note Published
10/30/2024
blur_on Resolution
2.27 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SODIUM ION, HEXAETHYLENE GLYCOL, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLOROPYRAZINECARBOXAMIDE

Original publication

import_contacts Title
X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel.
import_contacts Journal
Cell(Cambridge,Mass.) 2014
import_contacts DOI
10.1016/j.cell.2014.01.011
person Authors
Gouaux, E., Goehring, A., Bohlen, C.J., Baconguis, I., Julius, D.

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