PDB | 3g60 Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
label Keywords
p-glycoprotein, pgp, multidrug resistance, membrane protein, cyclic peptide
event_note Published
02/21/2024
blur_on Resolution
4.4 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
Original publication
import_contacts Title
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
import_contacts Journal
Science 2009
import_contacts DOI
10.1126/science.1168750
person Authors
Chittaboina, S., Zhang, Q., Zhuo, R., Weng, Y., Trinh, Y.T., Yu, J., Urbatsch, I.L., Ward, A., Harrell, P.M., Chang, G., Aller, S.G.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chittaboina, S., Zhang, Q., Zhuo, R., Weng, Y., Trinh, Y.T., Yu, J., Urbatsch, I.L., Ward, A., Harrell, P.M., Chang, G., Aller, S.G. , provided free of copyright via the Protein DataBank. View original data or read license terms.
