PDB | 9j40 Lysosome cholesterol sencing protein complex

Cryo-EM structure of lysosome cholesterol sencing protein complex

label Keywords
lipid binding protein
event_note Published
04/09/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 3-SULFOOXY-1H-INDOLE, CHOLESTEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose, TRYPTOPHAN

Original publication

import_contacts Title
Structural basis for cholesterol sensing of LYCHOS and its interaction with indoxyl sulfate.
import_contacts Journal
Nat Commun 2025
import_contacts DOI
10.1038/s41467-025-58087-9
person Authors
Wang, Z., He, J., He, Y., Yang, Y., Qian, H.

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