PDB | 9j40 Lysosome cholesterol sencing protein complex
Cryo-EM structure of lysosome cholesterol sencing protein complex
label Keywords
lipid binding protein
event_note Published
04/09/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 3-SULFOOXY-1H-INDOLE, CHOLESTEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose, TRYPTOPHAN
Original publication
import_contacts Title
Structural basis for cholesterol sensing of LYCHOS and its interaction with indoxyl sulfate.
import_contacts Journal
Nat Commun 2025
import_contacts DOI
10.1038/s41467-025-58087-9
person Authors
Wang, Z., He, J., He, Y., Yang, Y., Qian, H.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Wang, Z., He, J., He, Y., Yang, Y., Qian, H. , provided free of copyright via the Protein DataBank. View original data or read license terms.