PDB | 9iws Human phosphate channel XPR1
Cryo EM structure of human phosphate channel XPR1 in complex with IP7
label Keywords
phosphate channel, inositol pyrosphosphate, membrane protein, phosphate homeostasis, transport protein
event_note Published
12/18/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate
Original publication
import_contacts Title
Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1.
import_contacts Journal
Science 2024
import_contacts DOI
10.1126/science.adp3252
person Authors
Xia, Y., Zhang, X., Lu, Y., Zhou, L., Zhang, L., Zhang, Q., Guo, C.R., Qin, A., Yue, C.X., Yao, D., Cao, Y., Shen, Y., Li, S., Zhao, J., Cao, M., Yu, Y.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Xia, Y., Zhang, X., Lu, Y., Zhou, L., Zhang, L., Zhang, Q., Guo, C.R., Qin, A., Yue, C.X., Yao, D., Cao, Y., Shen, Y., Li, S., Zhao, J., Cao, M., Yu, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.