PDB | 9iws Human phosphate channel XPR1

Cryo EM structure of human phosphate channel XPR1 in complex with IP7

label Keywords
phosphate channel, inositol pyrosphosphate, membrane protein, phosphate homeostasis, transport protein
event_note Published
12/18/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate

Original publication

import_contacts Title
Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1.
import_contacts Journal
Science 2024
import_contacts DOI
10.1126/science.adp3252
person Authors
Xia, Y., Zhang, X., Lu, Y., Zhou, L., Zhang, L., Zhang, Q., Guo, C.R., Qin, A., Yue, C.X., Yao, D., Cao, Y., Shen, Y., Li, S., Zhao, J., Cao, M., Yu, Y.

Loading