PDB | 9eai Structure of nanobody AT206
Structure of nanobody AT206 in complex with the losartan-bound angiotensin II type I receptor (AT1R)
label Keywords
gpcr, at1r, nanobody, membrane protein
event_note Published
03/26/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[2-butyl-5-chloranyl-3-[[4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol, CHOLESTEROL HEMISUCCINATE, CHOLESTEROL
Original publication
import_contacts Title
Epitope-directed selection of GPCR nanobody ligands with evolvable function.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2025
import_contacts DOI
10.1073/pnas.2423931122
person Authors
Nemeth, G.R., Kanso, A., Liu, J., Kruse, A.C., Skiba, M.A., Canavan, C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Nemeth, G.R., Kanso, A., Liu, J., Kruse, A.C., Skiba, M.A., Canavan, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
