PDB | 9ctc SapNP reconstituted Human ABCB1

SapNP reconstituted Human ABCB1 in complex with Zosuquidar and ATP/Mg

label Keywords
abcb1, p-gp, inhibitor bound, nanoparticle, saposin, zosuquidar bound, membrane protein, translocase
event_note Published
03/05/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ADENOSINE-5'-TRIPHOSPHATE, Zosuquidar, UNKNOWN BRANCHED FRAGMENT OF PHOSPHOLIPID

Original publication

import_contacts Title
Structural insights into binding-site access and ligand recognition by human ABCB1.
import_contacts Journal
Embo J. 2025
import_contacts DOI
10.1038/s44318-025-00361-z
person Authors
Kurre, D., Le, L.T.M., Alam, A., Dang, P.X., Gadkari, V.V.

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