PDB | 9cc2 Mouse PI(4,5)P2-bound TRPML1 channel at 2.46 Angstrom resolution
Cryo-EM structure of mouse PI(4,5)P2-bound TRPML1 channel at 2.46 Angstrom resolution
label Keywords
trpml1, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, sphingomyelin
Original publication
import_contacts Title
TRPML1 gating modulation by allosteric mutations and lipids.
import_contacts Journal
Biorxiv 2024
import_contacts DOI
10.1101/2024.07.04.602033
person Authors
Jiang, Y., Zeng, W., Gan, N., Han, Y.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Jiang, Y., Zeng, W., Gan, N., Han, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.