PDB | 9b9y Structural mechanism of CB1R binding to peripheral and biased inverse agonists
Structural mechanism of CB1R binding to peripheral and biased inverse agonists
label Keywords
obesity, membrane protein, nanobody, signaling protein-immune system complex
event_note Published
01/01/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide
Original publication
import_contacts Title
Structural mechanism of CB 1 R binding to peripheral and biased inverse agonists.
import_contacts Journal
Nat Commun 2024
import_contacts DOI
10.1038/s41467-024-54206-0
person Authors
Kumari, P., Cinar, R., Kunos, G., Rosenbaum, D.M., Hassan, S.A., Dvoracsko, S., Iyer, M.R., Enos, M.D., Lim, D., Ramesh, K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Kumari, P., Cinar, R., Kunos, G., Rosenbaum, D.M., Hassan, S.A., Dvoracsko, S., Iyer, M.R., Enos, M.D., Lim, D., Ramesh, K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
