PDB | 9ayf Structure of human calcium-sensing receptor

Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent

label Keywords
calcium-sensing receptor, g-protein-coupled receptor, g protein, signal transduction, membrane protein
event_note Published
10/16/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOMETHYLTRYPTOPHAN, PHOSPHATE ION, CALCIUM ION, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, Lauryl Maltose Neopentyl Glycol

Original publication

import_contacts Title
Promiscuous G-protein activation by the calcium-sensing receptor.
import_contacts Journal
Nature 2024
import_contacts DOI
10.1038/s41586-024-07331-1
person Authors
Asher, W.B., Zhang, Z., Zuo, H., Eng, E., Wang, L., Park, J., Hu, G.B., Mendez, J., Lin, X., Frangaj, A., Clarke, O.B., Conigrave, A.D., Fan, Q.R., Grassucci, R., Javitch, J.A., Manning, J.J., Lu, G., Hendrickson, W.A., Lu, Z., Ye, J.

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