PDB | 9arx Local refinement of 5-HT2AR bound to 5-HT
Local refinement of 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
label Keywords
gpcr, g-protein coupled receptor, 5-ht2ar, serotonin, psychedelics, membrane protein
event_note Published
05/28/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
SEROTONIN
Original publication
import_contacts Title
The structural diversity of psychedelic drug actions revealed.
import_contacts Journal
Nat Commun 2025
import_contacts DOI
10.1038/s41467-025-57956-7
person Authors
Krumm, B.E., Kapolka, N.J., Kim, K., Jain, M.K., Gumpper, R.H., Sun, N., Fay, J.F., DiBerto, J.F., Xu, Z., Jin, J., Nichols, D.E., Sun, R., Roth, B.L., Kaniskan, H.U.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Krumm, B.E., Kapolka, N.J., Kim, K., Jain, M.K., Gumpper, R.H., Sun, N., Fay, J.F., DiBerto, J.F., Xu, Z., Jin, J., Nichols, D.E., Sun, R., Roth, B.L., Kaniskan, H.U. , provided free of copyright via the Protein DataBank. View original data or read license terms.
