PDB | 8zpn Cryo-EM strucutre of CXCR4 complexed
Cryo-EM strucutre of CXCR4 complexed with antagonist AMD3100
label Keywords
cxc motif chemokine receptor 4, antagonist, signaling protein
event_note Published
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filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, Plerixafor
Original publication
import_contacts Title
Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2025
import_contacts DOI
10.1073/pnas.2425795122
person Authors
Fang, X., Zhang, W., Xu, Y., Jiao, H., Qian, T., Pan, Q., Huang, Z., An, J., Zhou, J., Hu, H., Meng, Q., Sang, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Fang, X., Zhang, W., Xu, Y., Jiao, H., Qian, T., Pan, Q., Huang, Z., An, J., Zhou, J., Hu, H., Meng, Q., Sang, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.
