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      PDB | 8y6i P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc

      P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc

      label Keywords
      abc transporter, elacridar, p-glycoprotein, membrane protein
      event_note Published
      11/27/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      CHOLESTEROL, 1,2-Distearoyl-sn-glycerophosphoethanolamine, elacridar

      Original publication

      import_contacts Title
      Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules.
      import_contacts Journal
      Biochem.Biophys.Res.Commun. 2024
      import_contacts DOI
      10.1016/j.bbrc.2024.149855
      person Authors
      Senda, T., Ogasawara, S., Yasuda, S., Suzuki, K., Murata, T., Adachi, N., Kawasaki, M., Anzai, N., Moriya, T., Hamaguchi-Suzuki, N.

      Read article from Biochem.Biophys.Res.Commun.

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Senda, T., Ogasawara, S., Yasuda, S., Suzuki, K., Murata, T., Adachi, N., Kawasaki, M., Anzai, N., Moriya, T., Hamaguchi-Suzuki, N. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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