PDB | 8xqs Structure of human class T GPCR TAS2R14-DNGi complex

Structure of human class T GPCR TAS2R14-DNGi complex with Flufenamic acid.

label Keywords
gpcr, tas2r14, minigsg, flf, bitter receptor, signaling protein
event_note Published
10/16/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, CHOLESTEROL

Original publication

import_contacts Title
Bitter taste TAS2R14 activation by intracellular tastants and cholesterol.
import_contacts Journal
Nature 2024
import_contacts DOI
10.1038/s41586-024-07569-9
person Authors
Yang, C., Liu, S., Tan, Q., Liu, Z.J., Li, Y., Jiang, L., Wu, Y., Liu, J., Hua, T., Cheng, J., Zhao, F., Sun, Q., Sun, J., Yang, F., Ao, W., Gao, M., Wu, L., Hu, X., Wang, X., Pei, Y.

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