PDB | 8wpg Human calcium-sensing receptor

Human calcium-sensing receptor bound with cinacalcet in detergent

label Keywords
gpcr, allosteric modulator, activation, dimeric, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, TRYPTOPHAN, CALCIUM ION, PHOSPHATE ION, N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine

Original publication

import_contacts Title
Structural insights into asymmetric activation of the calcium-sensing receptor-G q complex.
import_contacts Journal
Cell Res. 2024
import_contacts DOI
10.1038/s41422-023-00892-2
person Authors
Yang, F., Meng, X., Ling, S., Xia, Z., Zhang, Y., Zhou, Y., Shi, C., Shi, P., Tian, C.

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