PDB | 8vzn FLVCR2 in the inward-facing state
Cryo-EM structure of FLVCR2 in the inward-facing state with choline bound
label Keywords
choline transporter, blood-brain barrier, membrane protein, mfs fold, transport protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLINE ION
Original publication
import_contacts Title
Structural and molecular basis of choline uptake into the brain by FLVCR2.
import_contacts Journal
Nature 2024
import_contacts DOI
10.1038/s41586-024-07326-y
person Authors
Yee, S.W., Giacomini, K.M., Mancia, F., Katewa, A., Mooney, S.W.J., Quick, M., Kloss, B., Gawda, T., Chen, T., Gil-Iturbe, E., Mukherjee, D., Huang, E.J., Arnold, T., Santander, N., Zhang, Z., Koo, K., Clarke, O.B., Cater, R.J., Kossiakoff, A.A., Reckers, A., Choy, B.C., Larpthaveesarp, A., Erramilli, S.K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Yee, S.W., Giacomini, K.M., Mancia, F., Katewa, A., Mooney, S.W.J., Quick, M., Kloss, B., Gawda, T., Chen, T., Gil-Iturbe, E., Mukherjee, D., Huang, E.J., Arnold, T., Santander, N., Zhang, Z., Koo, K., Clarke, O.B., Cater, R.J., Kossiakoff, A.A., Reckers, A., Choy, B.C., Larpthaveesarp, A., Erramilli, S.K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
