PDB | 8vvc Human ABC transporter (hABCC1)

Cryo-EM structure of human ABC transporter (hABCC1) with nucleotide-binding domain 2

label Keywords
cgamp exporter, multidrug-resistant protein, abc transporter, membrane protein
event_note Published
01/29/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands

Original publication

import_contacts Title
Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide cGAMP export.
import_contacts Journal
Immunity 2025
import_contacts DOI
10.1016/j.immuni.2024.12.002
person Authors
Borgnia, M.J., Shinde, O., Viverette, E.G., Zhang, Q., West, A.P., Stetson, D.B., Cambier, S., Yadav, G.P., Li, P., Sui, X., VanPortfliet, J.J., Boyer, J.A.

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