PDB | 8thr Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation
Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation
label Keywords
monoamine, neurotransmitter, synaptic vesicles, major facilitator superfamily, slc18, transport protein
event_note Published
05/08/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
Original publication
import_contacts Title
Structural mechanisms for VMAT2 inhibition by tetrabenazine.
import_contacts Journal
Elife 2024
import_contacts DOI
10.7554/eLife.91973
person Authors
Bahar, I., Coleman, J.A., Cheng, M.H., Dalton, M.P.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Bahar, I., Coleman, J.A., Cheng, M.H., Dalton, M.P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
