PDB | 8t6v Human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)

Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)

label Keywords
transmembrane, transport protein
event_note Published
12/25/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Original publication

import_contacts Title
Substrate binding and inhibition of the anion exchanger 1 transporter.
import_contacts Journal
Nat.Struct.Mol.Biol. 2023
import_contacts DOI
10.1038/s41594-023-01085-6
person Authors
Yang, S., Habib, R., Wacker, D., Hutchinson, K., Schlessinger, A., Capper, M.J., Mathiharan, Y.K., Zhang, B., Zhao, Y., Vatansever, S., Mezei, M., Osman, R., Stone, A.C., Zilberg, G.

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