PDB | 8t3o TUG-891 bound FFA4-Gq complex
Cryo-EM structure of the TUG-891 bound FFA4-Gq complex
label Keywords
gpcr, complex, agonist, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, PALMITIC ACID
Original publication
import_contacts Title
Structural basis for the ligand recognition and signaling of free fatty acid receptors.
import_contacts Journal
Sci Adv 2024
import_contacts DOI
10.1126/sciadv.adj2384
person Authors
Zhang, X., Tikhonova, I.G., Zhang, C., Guseinov, A.A., Li, K., Milligan, G., Jenkins, L.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Zhang, X., Tikhonova, I.G., Zhang, C., Guseinov, A.A., Li, K., Milligan, G., Jenkins, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
