PDB | 8t1b Full-length human TRPV4 in apo state
Cryo-EM structure of full-length human TRPV4 in apo state
label Keywords
transient receptor potential v family member 4, trp, channel, trpv4, trp channels, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(2~{R})-2-[(~{Z})-hexadec-9-enoyl]oxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propyl] (~{Z})-docos-13-enoate, (2R)-2-{[(4-O-hexopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-4-{[(25R)-5beta,14beta,17beta-spirostan-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, SODIUM ION
Original publication
import_contacts Title
Structure of human TRPV4 in complex with GTPase RhoA.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-39346-z
person Authors
Nadezhdin, K.D., Parthasarathy, A., Zhang, D.X., Neuberger, A., Sobolevsky, A.I., Talyzina, I.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Nadezhdin, K.D., Parthasarathy, A., Zhang, D.X., Neuberger, A., Sobolevsky, A.I., Talyzina, I.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
