PDB | 8s5u Thiamine-bound human SLC19A3 in outward-open state
Cryo-EM structure of thiamine-bound human SLC19A3 in outward-open state
label Keywords
slc19a3, vitamin transporter, thiamine transporter, mfs fold, nanobody complex, membrane protein
event_note Published
12/04/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Original publication
import_contacts Title
Structural basis of thiamine transport and drug recognition by SLC19A3.
import_contacts Journal
Nat Commun 2024
import_contacts DOI
10.1038/s41467-024-52872-8
person Authors
Jungnickel, K.E.J., Mostafavi, S., Fuhrmann, A., Spriestersbach, L., Steyaert, J., Gabriel, F., Low, C., Pardon, E.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Jungnickel, K.E.J., Mostafavi, S., Fuhrmann, A., Spriestersbach, L., Steyaert, J., Gabriel, F., Low, C., Pardon, E. , provided free of copyright via the Protein DataBank. View original data or read license terms.
