PDB | 8quc Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT1
Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT1
label Keywords
modulator, homotetramer, voltage-gated potassium channel, membrane protein, kv3.1, kcnc1
event_note Published
04/03/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(5R)-5-ethyl-3-[6-(3-methoxy-4-methyl-phenoxy)pyridin-3-yl]imidazolidine-2,4-dione, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, ZINC ION, CHOLESTEROL HEMISUCCINATE, POTASSIUM ION
Original publication
import_contacts Title
The binding and mechanism of a positive allosteric modulator of Kv3 channels.
import_contacts Journal
Nat Commun 2024
import_contacts DOI
10.1038/s41467-024-46813-8
person Authors
Treptow, W., Cirqueira, L., Liang, Q., Chi, G., Covarrubias, M., Sauer, D.B., Gunthorpe, M.J., Pilati, N., Zhi, L., Marasco, A., Large, C.H., Alvaro, G.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Treptow, W., Cirqueira, L., Liang, Q., Chi, G., Covarrubias, M., Sauer, D.B., Gunthorpe, M.J., Pilati, N., Zhi, L., Marasco, A., Large, C.H., Alvaro, G. , provided free of copyright via the Protein DataBank. View original data or read license terms.
