PDB | 8pkm Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex
Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex
label Keywords
membrane protein
event_note Published
12/18/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, (3-chloranyl-4-fluoranyl-phenyl)-[4-fluoranyl-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
Original publication
import_contacts Title
Discovery of a functionally selective serotonin 5-HT<sub>1A</sub> receptor agonist for the treatment of pain
import_contacts Journal
Biorxiv 2023
import_contacts DOI
10.1101/2023.09.11.557127
person Authors
Hove, T., Hubner, H., Inoue, A., Ullrich, A., Braz, J.M., Schneider, J., Stanek, M., Bottcher, B., Albert, T., Fink, E., Lober, S., Neu, E., Basbaum, A.J., Staffen, N., Weikert, D., Blahova, J., Shoichet, B.K., Bhardwaj, K., Gmeiner, P., Allikalt, A., Rasmussen, T., Rodriguez-Rosado, S.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Hove, T., Hubner, H., Inoue, A., Ullrich, A., Braz, J.M., Schneider, J., Stanek, M., Bottcher, B., Albert, T., Fink, E., Lober, S., Neu, E., Basbaum, A.J., Staffen, N., Weikert, D., Blahova, J., Shoichet, B.K., Bhardwaj, K., Gmeiner, P., Allikalt, A., Rasmussen, T., Rodriguez-Rosado, S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
