PDB | 8kfx Gi bound CCR8 complex

Gi bound CCR8 complex with nonpeptide agonist LMD-009

label Keywords
gpcr gi agonist, signaling protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
8-[[3-(2-methoxyphenoxy)phenyl]methyl]-1-(2-phenylethyl)-1,3,8-triazaspiro[4.5]decan-4-one

Original publication

import_contacts Title
Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8.
import_contacts Journal
Sci Adv 2024
import_contacts DOI
10.1126/sciadv.adj7500
person Authors
Wu, Y., Wang, L., Lin, X., Xu, Z., Xu, F., Wu, L., Jiang, S.

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