PDB | 8kdf Structure of LAT1-CD98hc
Structure of LAT1-CD98hc in complex with JPH203, focused on TMD
label Keywords
transporter, amino acid, complex, cancer, transport protein
event_note Published
02/26/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Nanvuranlat
Original publication
import_contacts Title
Structural basis of anticancer drug recognition and amino acid transport by LAT1.
import_contacts Journal
Nat Commun 2025
import_contacts DOI
10.1038/s41467-025-56903-w
person Authors
Kanai, Y., Warshamanage, R., Murshudov, G., Jin, C., Lee, Y., Yamashita, K., Ogasawara, S., Xu, M., Ohgaki, R., Murata, T., Nureki, O.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Kanai, Y., Warshamanage, R., Murshudov, G., Jin, C., Lee, Y., Yamashita, K., Ogasawara, S., Xu, M., Ohgaki, R., Murata, T., Nureki, O. , provided free of copyright via the Protein DataBank. View original data or read license terms.
