PDB | 8k7b Human ABCB6 W546A mutant (ADP/VO4-bound)
post-occluded structure of human ABCB6 W546A mutant (ADP/VO4-bound)
label Keywords
atp-binding cassette transporter mitochondrial transporter, post-occluded, adp/vo4-bound, abcb6, membrane protein, transport protein
event_note Published
07/26/2023
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, ADP ORTHOVANADATE, MAGNESIUM ION
Original publication
import_contacts Title
W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state.
import_contacts Journal
Commun Biol 2023
import_contacts DOI
10.1038/s42003-023-05339-3
person Authors
Kim, S., Jin, M.S., Jang, E., Choi, S.H., Park, J.G., Kim, J.W., Lee, S.S.
copyrightData provided by Research Collaboration for Structural Biology, Kim, S., Jin, M.S., Jang, E., Choi, S.H., Park, J.G., Kim, J.W., Lee, S.S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
