PDB | 8jzx SLC15A4 inhibitor complex
SLC15A4 inhibitor complex
label Keywords
endolysosomal transporter, protein transport-inhibitor complex
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, 2-(4-ethoxyphenyl)-N-[3-[(2R)-2-methylpiperidin-1-yl]propyl]quinoline-4-carboxamide
Original publication
import_contacts Title
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-42070-3
person Authors
Xie, M., Delacretaz, M., Bernaleau, L., Heinz, L.X., Chen, X., Kartnig, F., Dvorak, V., Koren, A., Superti-Furga, G., Zhang, H., Yang, M., Boeszoermenyi, A., Kubicek, S., Aletaha, D., Rebsamen, M., Zhang, S., Hopp, A.K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Xie, M., Delacretaz, M., Bernaleau, L., Heinz, L.X., Chen, X., Kartnig, F., Dvorak, V., Koren, A., Superti-Furga, G., Zhang, H., Yang, M., Boeszoermenyi, A., Kubicek, S., Aletaha, D., Rebsamen, M., Zhang, S., Hopp, A.K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
