PDB | 8jvi Structure of human TRPV4

Structure of human TRPV4 with antagonist A2

label Keywords
channel, membrane protein
event_note Published
07/24/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[(1~{S},5~{R})-3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone

Original publication

import_contacts Title
Structural Pharmacology of TRPV4 Antagonists.
import_contacts Journal
Adv Sci 2024
import_contacts DOI
10.1002/advs.202401583
person Authors
Xie, W., Liao, D., Lei, X., Tominaga, M., Ke, H., Lei, J., Huang, Z., Tang, Y., Guo, C., Fan, J.

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