PDB | 8ju6 Structure of human TRPV4

Structure of human TRPV4 with antagonist GSK279

label Keywords
channel, membrane protein
event_note Published
07/24/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1-({(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl}methyl)-1H-benzimidazole-6-carbonitrile

Original publication

import_contacts Title
Structural Pharmacology of TRPV4 Antagonists.
import_contacts Journal
Adv Sci 2024
import_contacts DOI
10.1002/advs.202401583
person Authors
Xie, W., Liao, D., Lei, X., Tominaga, M., Ke, H., Lei, J., Huang, Z., Tang, Y., Guo, C., Fan, J.

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