PDB | 8ju5 Structure of human TRPV4

Structure of human TRPV4 with antagonist A1

label Keywords
channel, membrane protein
event_note Published
07/24/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
4-[(3~{S},4~{S})-4-(aminomethyl)-1-(5-chloranylpyridin-2-yl)sulfonyl-4-oxidanyl-pyrrolidin-3-yl]oxy-2-fluoranyl-benzenecarbonitrile

Original publication

import_contacts Title
Structural Pharmacology of TRPV4 Antagonists.
import_contacts Journal
Adv Sci 2024
import_contacts DOI
10.1002/advs.202401583
person Authors
Xie, W., Liao, D., Lei, X., Tominaga, M., Ke, H., Lei, J., Huang, Z., Tang, Y., Guo, C., Fan, J.

Loading