PDB | 8jt8 Crystal structure of 5-HT2AR in complex with (R)-IHCH-7179
Crystal structure of 5-HT2AR in complex with (R)-IHCH-7179
label Keywords
gpcr, serotonin receptor, antipsychotic, membrane protein
event_note Published
11/13/2024
blur_on Resolution
2.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
MAGNESIUM ION, 1-(4-fluorophenyl)-4-[(7R)-2,5,11-triazatetracyclo[7.6.1.0^2,7.0^12,16]hexadeca-1(15),9,12(16),13-tetraen-5-yl]butan-1-one, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, PENTAETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Flexible scaffold-based cheminformatics approach for polypharmacological drug design.
import_contacts Journal
Cell 2024
import_contacts DOI
10.1016/j.cell.2024.02.034
person Authors
Chen, Z., Xu, P., Pei, G., Sun, F., Wan, X., Cheng, J., Wang, H., Yu, J., Huang, S., Xu, H.E., Zhang, B., Gu, S., Huang, H., Zhang, P., Wang, S., Zhou, Y., Fan, L.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chen, Z., Xu, P., Pei, G., Sun, F., Wan, X., Cheng, J., Wang, H., Yu, J., Huang, S., Xu, H.E., Zhang, B., Gu, S., Huang, H., Zhang, P., Wang, S., Zhou, Y., Fan, L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
