PDB | 8jpf NTSR1 in NTSR1-GRK2-Galpha(q) complexes
Focused refiment structure of NTSR1 in NTSR1-GRK2-Galpha(q) complexes
label Keywords
biased signaling, signaling protein
event_note Published
06/11/2023
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol
Original publication
import_contacts Title
GPCR activation and GRK2 assembly by a biased intracellular agonist.
import_contacts Journal
Nature 2023
import_contacts DOI
10.1038/s41586-023-06395-9
person Authors
Yin, W., Yang, D., Cai, X., Cheng, X., He, X., Wu, K., Zhao, F., Liu, H., Ji, Y., Wang, M.W., Gao, T., Li, J., Jiang, Y., Xu, H.E., Li, X., Duan, J., Lin, S., Yuan, Q., Zhu, S.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Yin, W., Yang, D., Cai, X., Cheng, X., He, X., Wu, K., Zhao, F., Liu, H., Ji, Y., Wang, M.W., Gao, T., Li, J., Jiang, Y., Xu, H.E., Li, X., Duan, J., Lin, S., Yuan, Q., Zhu, S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
