PDB | 8jlh Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam
Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam
label Keywords
synaptic vesicle, epilepsy, transport protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose
Original publication
import_contacts Title
Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
import_contacts Journal
Nat Commun 2024
import_contacts DOI
10.1038/s41467-024-47322-4
person Authors
Yamagata, A., Dohmae, N., Terada, T., Shirouzu, M., Suzuki, T., Ito, K.
copyrightData provided by Research Collaboration for Structural Biology, Yamagata, A., Dohmae, N., Terada, T., Shirouzu, M., Suzuki, T., Ito, K. , provided free of copyright via the Protein DataBank. View original data or read license terms.