PDB | 8jlh Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam

Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam

label Keywords
synaptic vesicle, epilepsy, transport protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose

Original publication

import_contacts Title
Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.
import_contacts Journal
Nat Commun 2024
import_contacts DOI
10.1038/s41467-024-47322-4
person Authors
Yamagata, A., Dohmae, N., Terada, T., Shirouzu, M., Suzuki, T., Ito, K.

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