PDB | 8jip GLP-1R/GCGR dual agonist MEDI0382-bound human GLP-1R-Gs complex
Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GLP-1R-Gs complex
label Keywords
g protein-coupled receptor, ligand recognition, receptor activation, unimolecular dual agonist, structural protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
N-hexadecanoyl-L-glutamic acid
Original publication
import_contacts Title
Structural analysis of the dual agonism at GLP-1R and GCGR.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2023
import_contacts DOI
10.1073/pnas.2303696120
person Authors
Ying, T., Li, Y., Chang, R., Zhou, Q., Dai, A., Zhao, F., Wang, M.W., Wu, B., Cong, Z., Yang, D.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Ying, T., Li, Y., Chang, R., Zhou, Q., Dai, A., Zhao, F., Wang, M.W., Wu, B., Cong, Z., Yang, D. , provided free of copyright via the Protein DataBank. View original data or read license terms.
