PDB | 8j4f Structure of human Nav1.7

Structure of human Nav1.7 in complex with Hardwickii acid

label Keywords
inhibitor complex., membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, (4~{a}~{R},5~{S},6~{R},8~{a}~{R})-5-[2-(furan-3-yl)ethyl]-5,6,8~{a}-trimethyl-3,4,4~{a},6,7,8-hexahydronaphthalene-1-carboxylic acid, CHOLESTEROL HEMISUCCINATE, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Original publication

import_contacts Title
Structural mapping of Na v 1.7 antagonists.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-38942-3
person Authors
Wang, K., Pan, X., Huang, G., Huang, J., Jin, X., Wu, Q., Fan, X., Li, J., Yan, N.

Loading