PDB | 8hvi Activation mechanism of GPR132 by compound NOX-6-7

Activation mechanism of GPR132 by compound NOX-6-7

label Keywords
gpcr, gpr132, membrane protein
event_note Published
06/25/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid

Original publication

import_contacts Title
Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
import_contacts Journal
Nat Metab 2023
import_contacts DOI
10.1038/s42255-023-00899-4
person Authors
Gao, M.X., Zhao, X.Y., Ding, J.H., Dou, X.D., Sun, J.P., Sha, X.Y., Zhang, C.F., Hao, Y., Ji, Z.W., Gao, J.R., Liu, Y.M., Wang, J.L., Ding, W., Zhang, C., Yu, X., Huo, T.Y., Cheng, J., Li, Y., Jiao, N., Wang, S.H., Xu, G.F., Zhang, W.H.

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