PDB | 8hnh Cryo-EM structure of human OATP1B1 in complex with simeprevir
Cryo-EM structure of human OATP1B1 in complex with simeprevir
label Keywords
transporter, oatp1b1, organic anion transporting peptide, membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-({7-methoxy-8-methyl-2-[4-(1-methylethyl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-5-methyl-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a(1H)-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose
Original publication
import_contacts Title
Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
import_contacts Journal
Cell Res. 2023
import_contacts DOI
10.1038/s41422-023-00870-8
person Authors
Nan, J., Zhang, W., Xiao, Y., Yuan, Y., Wang, J., Song, W., Zhang, Y., Liu, H., Wei, F., Shan, Z., Yang, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Nan, J., Zhang, W., Xiao, Y., Yuan, Y., Wang, J., Song, W., Zhang, Y., Liu, H., Wei, F., Shan, Z., Yang, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.
