PDB | 8gti Corticotropin-releasing hormone receptor 1(CRF1R)
Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL
label Keywords
membrane protein
event_note Published
11/20/2024
blur_on Resolution
2.2 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
OLEIC ACID, 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine
Original publication
import_contacts Title
Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
import_contacts Journal
Exp.Mol.Med. 2023
import_contacts DOI
10.1038/s12276-023-01082-1
person Authors
Kim, H., Kim, K.H., Chang, N., Ha, G.E., Lee, S.J., Lee, J., Kim, B.M., Kim, S.H., Lim, T., Cho, H.S., Cheong, E., Park, S., Kim, H.J., Kim, J.W., Lee, J.Y., Abrahamsson, A., Park, J., Cho, Y., Kim, B.W.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Kim, H., Kim, K.H., Chang, N., Ha, G.E., Lee, S.J., Lee, J., Kim, B.M., Kim, S.H., Lim, T., Cho, H.S., Cheong, E., Park, S., Kim, H.J., Kim, J.W., Lee, J.Y., Abrahamsson, A., Park, J., Cho, Y., Kim, B.W. , provided free of copyright via the Protein DataBank. View original data or read license terms.
