PDB | 8g59 TUG891 bound GPR120-Giq complex

Cryo-EM structure of the TUG891 bound GPR120-Giq complex

label Keywords
gpcr, gpr120, complex, fatty acid hormones, membrane protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid

Original publication

import_contacts Title
Unsaturated bond recognition leads to biased signal in a fatty acid receptor.
import_contacts Journal
Science 2023
import_contacts DOI
10.1126/science.add6220
person Authors
Huang, S.M., Zhang, H.Q., Sun, J.P., Wang, Q.L., Xiao, P., Shen, D.D., Chen, L.N., Guo, S.C., Chen, J., Feng, S., Guo, Y., Zhang, Y., Tao, X.N., Du, Y.Q., Wang, C., Zhang, C., Cheng, J., Zhong, Y.N., Yu, X., Xu, H.E., Mao, C., Li, G.Y., Liu, M.X., Yang, Z.S., He, Q.T., Shang, P., He, Y.H., Zhang, D.L., Qin, J.

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