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      PDB | 8g4o Native GABA-A receptor

      Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with didesethylflurazepam and endogenous GABA

      label Keywords
      ligand-gated ion channel, cys-loop receptor, neurotransmitter receptor, membrane protein
      event_note Published
      11/13/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      GAMMA-AMINO-BUTANOIC ACID, (5M)-1-(2-aminoethyl)-7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose

      Original publication

      import_contacts Title
      Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology.
      import_contacts Journal
      Nature 2023
      import_contacts DOI
      10.1038/s41586-023-06556-w
      person Authors
      Sun, C., Zhu, H., Gouaux, E., Clark, S.

      Read article from Nature

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Sun, C., Zhu, H., Gouaux, E., Clark, S. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline8g4o_default_dppc

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