PDB | 8fob Human TRPV6 in the open state
Cryo-EM structure of human TRPV6 in the open state
label Keywords
transient receptor potential v family member 6, trp, human, channel, apo state, open, trpv6, trp channels, cancer, oncochannel, membrane protein
event_note Published
06/19/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL HEMISUCCINATE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION
Original publication
import_contacts Title
Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-38352-5
person Authors
Trofimov, Y.A., Nadezhdin, K.D., Krylov, N.A., Neuberger, A., Yelshanskaya, M.V., Sobolevsky, A.I., Efremov, R.G.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Trofimov, Y.A., Nadezhdin, K.D., Krylov, N.A., Neuberger, A., Yelshanskaya, M.V., Sobolevsky, A.I., Efremov, R.G. , provided free of copyright via the Protein DataBank. View original data or read license terms.
