PDB | 8fhi Wildtype rabbit TRPV5 in nanodiscs

Wildtype rabbit TRPV5 in nanodiscs in complex with oleoyl coenzyme A, Open stated

label Keywords
trpv5, trp channel, oleoyl coenzyme a, open state, membrane protein
event_note Published
12/14/2022
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ERGOSTEROL, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate

Original publication

import_contacts Title
Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-41577-z
person Authors
Moiseenkova-Bell, V., Lee, B.H., Rohacs, T., De Jesus Perez, J.J.

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