PDB | 8ffo Wildtype rabbit TRPV5

Cryo-EM structure of wildtype rabbit TRPV5 with PI(4,5)P2 in nanodiscs

label Keywords
trpv5, trp channel, pi(4, 5)p2, membrane protein
event_note Published
12/09/2022
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ERGOSTEROL, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate

Original publication

import_contacts Title
Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-41577-z
person Authors
Moiseenkova-Bell, V., Lee, B.H., Rohacs, T., De Jesus Perez, J.J.

Loading