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      PDB | 8f2s Torpedo nicotinic acetylcholine receptor

      Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with rocuronium, pore-blocked state

      label Keywords
      acetylcholine receptor, nicotinic receptor, torpedo, cys-loop receptor, ion channel, muscle-type nicotinic receptor, transport protein-inhibitor complex, neuromuscular blocker, inhibitor
      event_note Published
      05/14/2025
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      rocuronium, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose, nonane

      Original publication

      import_contacts Title
      Structural interplay of anesthetics and paralytics on muscle nicotinic receptors.
      import_contacts Journal
      Nat Commun 2023
      import_contacts DOI
      10.1038/s41467-023-38827-5
      person Authors
      Teng, J., Goswami, U., Hibbs, R.E., Rahman, M.M.

      Read article from Nat Commun

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Teng, J., Goswami, U., Hibbs, R.E., Rahman, M.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline8f2s_default_dppc

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