PDB | 8f1c Voltage-gated potassium channel Kv3.1
Voltage-gated potassium channel Kv3.1 with novel positive modulator (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one (compound 4)
label Keywords
ion channel, positive modulator, voltage gated, voltage gated potassium channel, transport protein
event_note Published
11/04/2022
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
ZINC ION, (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION
Original publication
import_contacts Title
Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2023
import_contacts DOI
10.1073/pnas.2220029120
person Authors
Soisson, S.M., Kostas, J., Li, Y., Kraus, R.L., Stachel, S.J., Ginnetti, A.T., Wang, D., Hong, M.R., Ishchenko, A., Zhang, X.J., Marino, M.J., Santarelli, V.P., Brooun, A., Klein, D.J., Chen, Y.T., Strickland, C., Gomez-Llorente, Y.
copyrightData provided by Research Collaboration for Structural Biology, Soisson, S.M., Kostas, J., Li, Y., Kraus, R.L., Stachel, S.J., Ginnetti, A.T., Wang, D., Hong, M.R., Ishchenko, A., Zhang, X.J., Marino, M.J., Santarelli, V.P., Brooun, A., Klein, D.J., Chen, Y.T., Strickland, C., Gomez-Llorente, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
